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Chapter
1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
References
CHAPTER 6. EVALUATIONS OF DRUG ABUSE TREATMENT
6.1
Introduction
Our goals for this chapter were similar
to those in the previous chapter on alcoholism treatments. Based on
a review of the extant literature, we hoped to learn the answers to
the following questions:
(1)
What treatments are being used to treat drug abusers?
(2)
Are these treatments effective? Do they work?
(3)
Which treatments are the most cost effective?
(4)
What are the benefit/cost ratios for these treatments?
(5)
Which treatments are the most effective for the different
types of patients?
At best, we were only able to find
partial answers to these questions. The reason for this is that
evaluation of drug abuse treatment effectiveness is very complex,
involving an assessment of the nature of treatment provided, the
problems and characteristics of clients, and the multiple outcomes
attributable to interaction between treatments and clients (Hubbard
et al. 1989). Because treatment programs have different goals, they
use different outcomes to measure success. All of the programs seek
to reduce or eliminate drug use among patients and many seek to
lessen criminal activity as well. Some programs attempt to increase
their patients’ employment and earning opportunities, while others
try to change their patients’ lifestyles, social behavior, and
mental health. This review will focus on the program’s ability to
reduce drug use and criminality and to improve patients’ employment
and earnings. Patients, their families, and health care
administrators are particularly interested in the decline in drug
use because of the health benefits, the reduction of stress, and the
associated decline in diseases such as AIDS, TB, and hepatitis
spread by the use of needles (McLellan, Woody, and Metzger 1996).
Taxpayers and government officials are, perhaps, more interested in
the effects of treatments on criminality, employment and earnings
for obvious reasons.
Part of the complexity of the study of
drug abuse treatment effectiveness arises from the diversity of
approaches and settings in which treatment occurs. Drug abuse
treatment is provided in a number of modalities by hospitals,
community public health agencies, and a variety of independent
organizations (Hubbard et al. 1989). Prior to 1990, there were four
major modalities (detoxification programs, methadone maintenance
programs, residential drug free, and outpatient drug free) and
effectiveness results were frequently reported at this level. In
the 1990s, a number of new modalities were introduced and some of
them have recently been evaluated (NIDA 1999). Comparisons of the
relative effectiveness of drug abuse modalities is difficult because
they have different goals and outcome measures, they provide
different treatment services, and they serve different types of
patients (DeLeon 1984, Hubbard et al. 1989, and NIDA 1999).
The outline of the chapter is as
follows. Section 6.2 discusses the major types of drug abuse
treatments and the various types of modalities. In the next
section, we outline the major methodological problems involved in
estimating the effectiveness of drug abuse treatments. Section 6.4
reviews the literature on the effectiveness of drug abuse
treatments. We begin with an overview of the data sources and the
overall effectiveness of such treatments. Then we consider modality
effectiveness. Studies have shown that the modalities treat
different types of clients and that outcomes are sensitive to the
problems and characteristics of clients. We shall investigate this
literature next. After this, we shall examine the literature on the
effects and determinants of length of treatment on program
effectiveness. This is followed by a discussion of the
effectiveness of individual treatment and program components. We
shall also discuss the “MATCHING” hypothesis. The section ends with
a discussion of the problems of relapse and readmission.
In Section 6.5 we shall review the
sparse literature on the cost-effectiveness of drug abuse treatment
programs. The few existing benefit/cost studies of drug abuse
treatment programs will be considered in the next section. Section
6.6 critically reviews some recent benefit/cost studies of state
drug abuse programs from the taxpayer’s point of view. The final
section summarizes our findings and conclusions on drug abuse
treatment evaluations.
6.2
Drug Abuse Treatments and Modalities
According to Anglin and Hser (1990),
there is no simple cure for drug dependence. Drug dependence is a
chronic condition, and relapse is often the rule. Many biological,
socio-cultural, economic, and psychological factors are believed to
contribute to drug abuse. For this reason, the treatment of drug
abuse is not simply a medical issue; it involves a wide spectrum of
social considerations. Because of the complexity of addiction, drug
addiction treatment involves many components. Some of those
components focus directly on the individual’s drug use, but others
focus on restoring the addicted individual to productive membership
in the family and society (NIDA 1999). Treatment for drug abuse and
addiction is delivered in many different settings, using a variety
of behavioral and pharmacological approaches.
6.2.1 Drug Abuse Treatment Modalities
Research studies on drug addiction have
typically classified treatment programs into several general types
or modalities (NIDA 1999). These include the following:
(1)
Methadone Maintenance Treatment for opiate addicts
usually is conducted in outpatient settings. These programs use a
long-acting synthetic opiate medication, usually methadone or LAAM,
administered orally for a sustained period at a dosage sufficient to
prevent opiate withdrawal, block the effects of illicit opiate use,
and decrease craving.
(2)
Narcotic Antagonist Treatment Using Naltrexone
for opiate addicts usually is conducted in outpatient settings.
Naltrexone is a long-acting synthetic opiate antagonist that blocks
the effects of self-administered opiates, including euphoria.
(3)
Outpatient Drug-Free Treatment programs differ in the
types and intensity of services offered, such as drug education and
counseling. Such treatment costs less than residential or inpatient
treatment and often is more suitable for individuals who are
employed or who have extensive social supports.
(4)
Long-Term Residential Treatment provides care 24 hours
per day, generally in non-hospital settings. The best-known
residential treatment model is the therapeutic community (TC), which
focuses on the “re-socialization” of the individual and uses the
program’s entire “community” as active components of treatment.
Addiction is viewed in the context of an individual’s social and
psychological deficits, and treatment focuses on developing personal
accountability and responsibility and socially productive lives.
Some residential treatment programs employ other models, such as
cognitive-behavioral therapy.
(5)
Short-Term Residential Programs
provide intensive but
relatively brief residential treatment based on a modified 12-step
approach. These programs were originally designed to treat alcohol
patients, but during the cocaine epidemic of the mid-1980’s, many
began to treat illicit drug abuse and addiction.
(6)
Medical Detoxification is a process whereby
individuals are systematically withdrawn from addicting drugs in an
inpatient or outpatient setting, typically under the care of a
physician. Detoxification is sometimes called a distinct treatment
modality but is more appropriately considered a precursor of
treatment, because it is designed to treat the acute physiological
effects of stopping drug use.
(7)
Prison-Based Treatment Programs
Offenders with
drug disorders may encounter a number of treatment options while
incarcerated, including didactic drug education classes, self-help
programs, and treatment based on therapeutic community or
residential milieu therapy models.
(8)
Community-Based Treatment for Criminal Justice Populations
A number of
criminal justice alternatives to incarceration have been tried with
offenders who have drug disorders, including limited diversion
programs, pretrial release conditional on entry into treatment, and
conditional probation with sanctions. For example, drug courts
mandate and arrange for drug addiction treatment, actively monitor
progress in treatment, and arrange for other services to
drug-involved offenders. The Treatment Accountability and Safer
Communities (TASC) program provides an alternative to incarceration
by addressing the multiple needs of drug-addicted offenders in a
community-based setting. These programs include counseling, medical
care, parenting instruction, family counseling, school and job
training, and legal and employment services. The key features of
TASC include (1) coordination of criminal justice and drug
treatment; (2) early identification, assessment, and referral of
drug-involved offenders; (3) monitoring offenders through drug
testing; and (4) use of legal sanctions as inducements to remain in
treatment.
6.2.2 Drug Abuse Treatments
Most treatment programs usually provide
a combination of service components besides their modality-specific
treatment. The following treatment components have been identified
by Anglin and Hser (1990) and the National Institute of Drug Abuse
(1999).
(1)
Drug Counseling is the primary support service provided to
clients in most drug-treatment programs and is common across all
modalities. Drug counseling focuses on assisting the client in
practical problem solving for day-to-day living.
(2)
Drug Education contributes to the client’s understanding of
the biological, familial, psychological, and social factors that
contribute to drug dependence.
(3)
Pharmacotherapy interventions with serious drug dependence
typically involve a period of detoxification for the purpose of
medically managing drug withdrawal systems. Agents such as
desiprimine and bromocriptine have been used to treat depression
with dysfunctional levels of cocaine use. Long-term use of narcotic
antagonists such as naltrexone or clonidine have been used to treat
heroin addiction. Methadone substitution for illicit opiate
dependence is perhaps the most lengthy pharmacotherapy applied in
drug treatment.
(4)
Psychotherapy components vary widely across the programs.
The unit of the intervention may be the client, the client and
spouse, or the family. Group counseling is commonly used.
(5)
Education and Vocational services are often provided because
of clients educational, employment, and legal problems. Job skill
training can enhance employment and earnings opportunities.
(6)
Urine testing provides one objective measure of compliance
with the treatment goals of reducing primary drug use. Such testing
is common in all modalities.
(7)
Relapse-prevention training can be used to insulate the
carefully cultivated attitudes, skills, and intentions derived from
the treatment process from individual and community influences. The
relapse prevention approach to the treatment of cocaine addiction
consists of a collection of strategies intended to enhance
self-control (NIDA 1999).
(8)
Social and Community Support assists recovery from drug
dependence during treatment after discharge. This includes
self-help or mutual support organizations like Narcotics Anonymous
and Cocaine Anonymous. Group homes can provide a useful
intermediate step from residential care to community care.
(9)
The Matrix Model draws heavily from other treatment
approaches. It includes relapse prevention training, family and
group therapies, drug education and self-help participation. The
therapist functions simultaneously as teacher and coach, fostering a
positive encouraging relationship with the patient and using that
relationship to reinforce positive behavior change.
(10)
Supportive-Expressive Psychotherapy has two main components:
supportive techniques to help patients feel comfortable in
discussing their personal experiences and expressive techniques to
help patients identify and work through interpersonal relationship
issues. Special attention is paid to the role of drugs in relation
to problem feelings and behaviors, and how problems may be solved
without recourse to drugs.
(11)
Motivational Enhancement Therapy is a client-centered
counseling approach for initiating behavior change by helping
clients to resolve ambivalence about engaging in treatment and
stopping drug use. This approach employs strategies to evoke rapid
and internally motivated change in the client, rather than guiding
the client stepwise through the recovery process.
6.3
Methodological Problems in Evaluating Drug Abuse Treatments
The number of evaluation studies of
drug abuse treatment programs has increased rapidly since the early
1970s. These studies vary in scope and methodology, which makes it
difficult to interpret and compare their results (French 1995 and
Anglin and Hser 1990). The methodological problems involved in
evaluating drug abuse problems are quite similar to those in
evaluating alcoholism treatments, which were discussed in Section
5.3. Therefore, only a brief summary of these problems will be
presented in this section.
Problem 1. Standardizing Treatment
Protocols
There is widespread disagreement among
clinicians and researchers with respect to the causes of drug
addiction and how it should be treated. Therefore, treatments,
processes, and procedures vary from program to program. Evaluation
studies of drug abuse programs rarely provide detailed information
on these components so we are only beginning to learn the relative
effectiveness of these components (see Section 6.4.5 below).
Recently, the National Institute of Drug Abuse (1999) put out a
manual explaining how to measure and improve costs,
cost-effectiveness, and cost benefit for substance abuse treatment
programs based on a cost-procedure-process-outcome analysis (CPPOA)
model. The manual is intended to help program managers understand
why their programs are effective and to find the cost-effectiveness
of individual processes and procedures so that programs can be
improved.
Problem 2. Standardized Outcome Measures
The primary goal of most drug abuse
treatment programs is abstinence or at the very least reduction in
drug use. But studies define and measure success with respect to
abstinence and reduced drug use in different ways, making it
difficult to compare the relative effectiveness of the programs.
Drug abuse programs have a number of other goals and associated
output measures including: “decreased levels of illegal activities
such as drug trafficking, property crime, or prostitution; increased
employment and decreased reliance on social service agencies;
improved social and family functioning; improved psychological
functioning, and decreased mortality and improved physical health” (Anglin
and Hser, 1990, pp. 415-416). Because program objectives and output
measures are not identical across programs, it is difficult to
measure their relative effectiveness.
Problem 3. Patient Variation
Over time we have learned more about
the heterogeneous nature of the drug-dependent population. We have
learned that certain types of patients self-select into different
types of drug abuse modalities and types of treatments (Anglin and
Hser 1990). Some clients respond to treatments better than others
and some patient characteristics are significantly correlated with
successful outcomes (see Section 6.4.3 below). It is difficult to
separate treatment effects from patient variation when comparing the
effectiveness of different programs.
Problem 4. Costs of Treatments
Average costs per patient are typically
reported (if at all) at the program level rather than actual
individual patient costs. Because most programs tailor treatments
to individuals, and individuals remain in treatment for different
lengths of time, the average cost per patient is a poor proxy for
actual patient cost (NIDA 1999). In addition, most evaluation
studies ignore indirect costs such as individual’s transportation
expenses, lost work time, donated time and equipment, and care
taking (French 1995). The omission of such costs makes it difficult
to estimate the cost-effectiveness or the cost-benefits of drug
abuse programs.
Problem 5. Research Design
Like alcoholism treatment evaluations,
drug abuse treatment evaluations do not use the experimental design,
which randomly assigns patients to experimental patient groups and
to a control group which does not receive treatment services,
because it is considered unethical to deny services to drug abusers
(Anglin and Hser 1990). In the absence of randomly selected “no
treatment” control groups, it is impossible to determine the “true”
effectiveness of drug abuse treatments.
Random assignment reduces or eliminates
the problem of patient variation discussed above. There have been a
few attempts to randomly assign patients in drug abuse studies, but
many patients refuse random assignment and attrition rates have been
so high that the results cannot be trusted (Anglin and Hser 1990).
Many of the early 1970s evaluation
studies of drug abuse programs did not include control groups. For
reasons discussed earlier, we have little confidence in these
studies’ findings. Later studies have used the pre/post research
design with patients serving as their “own” control group. These
studies produce results that are favorable biased because of the
“ramp up” and “regression-to-the-mean” and “spontaneous recovery”
problems discussed earlier.
A few studies have used a matched
control group drawn from participant dropouts or waiting lists.
Unfortunately, we cannot be sure that individuals chosen from these
sources have the same motivation to change even if they are matched
on other patient characteristics. Finally, there are a few natural
experiment studies where the control group seems quite comparable to
the treatment group (Anglin and Hser 1990). These studies come
closer to measuring the “true” effectiveness of drug abuse treatment
programs than the other evaluations.
Problem 6. The “Ramp Up Effect” and
“Regression-to-the-Mean Problem
Anglin and Hser (1990), French (1995),
and Estee and Nordlund (2001) have noted that the abnormally high
levels of drug use, crime, or both among drug abusers in the period
just prior to treatment might cause the observed “improvement” in
the post-period to represent no more than a “regression-to-the-mean
effect, particularly when the pre-treatment period was short. Also,
the crisis resulting from the high levels of drug use and crime
might cause the individuals to seek treatment or to change their
behavior without treatment (i.e., “spontaneous recovery”).
Problem 7. Follow-Up Analysis Problems
Drug abuse evaluation follow-up periods
tend to be short (6 months or one year). Studies using no control
group or “own” control group research designs tend to produce highly
favorable results in short follow-up periods because of the
“regression-to-the-mean” and “spontaneous recovery effects”.
Studies with longer follow-ups (2 years or more) provide a better
indication of a program’s effectiveness. Follow-ups also face the
problem of sample selection due to high attrition rates in drug
abuse programs (which often exceed 50%).
Problem 8. The Relapse Issue
Drug dependence is a chronic illness
and many patients that successfully complete drug abuse treatments
will relapse and later re-enter new drug-abuse treatment programs.
Most drug abuse evaluations ignore the issue of readmission. They
focus on individual treatment episodes. Without tracking patients
who return for more treatment, treatment cost and effectiveness
measures could be seriously biased (French 1995). Observed
differences in abuse treatment effectiveness could represent
different mixes of new and readmitted patients rather than “true”
treatment effects.
Problem 9. Spontaneous Recovery
We know that some drug abusers recover
(i.e., lessen their drug use and reduce their health care
expenditures) without treatment (Estee and Nordlund 2001) and
follow-up studies often show some degree of improvement for drug
abusers that receive only minimal treatment (Anglin and Hser 1990).
For these reasons, it is difficult to accept at face value the
highly favorable results reported by evaluation studies that have no
control group or that use an “own-patient” control group. If a
spontaneous recovery effect is present, their estimates of success
are biased upward by an unknown amount.
Problem 10. Statistical Analysis
Most research data obtained in
drug-treatment evaluation have been analyzed at the descriptive and
comparative level. Simple descriptive analysis of means can detect
average changes in outcome variables between periods, but it cannot
explain or predict the causes of the changes. We need more advanced
statistical techniques such as multivariate regression analysis to
help explain why a certain result occurred (French 1995).
Multivariate analysis can be used to estimate the effects of patient
characteristics and program components on post-treatment outcome
measures. With advanced statistical techniques, we can begin to
learn why programs and individual drug abuse treatments are
effective. Over time, drug-treatment evaluations have become more
sophisticated in terms of research design and statistical analysis,
but there is still a long way to go before we are able to measure
the “true” effectiveness of drug abuse treatment programs.
6.4
The Effectiveness of Drug Abuse Treatments
A considerable body of evaluative
research on the treatment of drug abuse has been generated over the
past thirty years, by clinical experience and project research and
from three large evaluative studies. The Drug Abuse Reporting
Program (DARP) was the first comprehensive, nationally based
evaluation of drug abuse treatment effectiveness. DARP examined the
admission records of over 44,000 clients in 52 NIDA-supported
agencies during the period from 1969 to 1974 (Hubbard et al. 1989).
At that time, the drug of choice was opiates. Effectiveness
measures were reported in DARP studies based on one, six, and
twelve-year follow-ups.
The second national evaluation study,
Treatment Outcome Prospective Study (TOPS), was also funded by the
NIDA. The TOPS study included 11,750 clients in three annual
admission cohorts – 1979, 1980, and 1981. This study collected more
information about the nature of drug abuse treatment and the
characteristics and behavior of abusers prior to treatment.
Evaluation reports were conducted during treatment and based on,
one, two, three, and five-year follow-ups. Most TOPS studies use
the pre/post research design with no separate control group. The
studies do report outcomes for patients who received minimal (less
than 3 months) treatments. The TOPS research also includes studies
of the outcomes for clients involved with the criminal justice
system, particularly those referred to treatment by the Treatment
Alternatives to Street Crime (TASC) programs (Hubbard, Rochal,
Craddock, and Cavanaugh, 1984). The TOPS studies included far more
non-opioid drug abusers than did the DARP studies.
Finally, the NIDA supported the Drug
Abuse Treatment Outcome Study (DATOS) which tracked 10,010
admissions to 96 programs in 11 cities for 1991-1993. This includes
2,774 admissions to long-term residential programs; 2,574 to
outpatient drug free programs, 3,122 to short-term inpatient
programs, and 1,540 to outpatient methadone treatment (DATOS
2003b). DATOS analysis was limited to clients who had stayed in
treatment for at least a month. Evaluations were based on one and
five year follow-ups. The DATOS studies did not include a control
group. DATOS collected a large amount of data on clients,
treatments, and the program environment, which was intended to help
us understand how drug abuse treatment works (Franey and Ashton
2002).
Literally hundreds of drug abuse
treatment effectiveness studies have been published. There was no
way to incorporate all of these studies in this review. Our
analysis of drug abuse treatment effectiveness draws heavily from
seven survey papers (Tims and Ludford 1984, Hubbard et al. 1989,
Anglin and Hser (1990), McLelland, Woody, and Metzger 1996, NIDA
1999, Franey and Ashton 2002, and numerous DATOS sources 2003). A
number of individual studies were also reviewed and they will be
incorporated into the discussion.
6.4.1 The Overall Effectiveness of Drug
Abuse Treatments
Early in the literature, most
researchers concluded that, in general, drug abuse treatments are
effective in reducing patient’s drug use and criminal behavior, but
somewhat less successful in improving patient’s social behavior,
employment opportunities and mental health. For example, see the
statements by Joffe, Hubbard et al., Sevay, and Tims and Holland in
the NIDA volume edited by Tims and Luford (1984).
According to Hubbard et al. (1989), the
body of research emerging from the DARP study provides convincing
evidence of the effectiveness of drug abuse treatment in
community-based settings. Significant reductions in drug use were
reported. For example, 82% of DARP clients reported they frequently
used heroin in the year before treatment. One year after treatment,
only 63% reported any opioid use and 47% reported daily use. Six
years after treatment, only 42% reported any use and 25% reported
daily use. Between 6 to 12 years after treatment, 23% increased
their frequency of opioid use and 23% decreased their frequency of
opioid use or stopped entirely.
Although fewer in number, cocaine users
in the DARP sample also reduced their consumption following
treatment. During the pre-treatment period, 38% of their sample of
opioid users has used cocaine. One to six years after treatment
only 18 to 32% reported using cocaine. However, in the 12 year
follow-up, 39% said they used cocaine. Finally, the DARP studies
indicated that patient’s use of marijuana and alcohol increased
after treatment raising the possibility that these drugs were being
substituted for opioids, a troubling prospect. The DARP studies
reported a significant decline in criminal activity following
treatment. We shall review these findings in our discussion of
modality effectiveness presented later.
TOPS studies also reported significant
declines in drug use and criminal activity following drug abuse
treatment (Hubbard et al. 1989). TOPS compared the use of four
types of drugs (heroin, cocaine, psychotherapeutic drugs, and
marijuana) for the year prior to treatment, during the treatment
period, and one and five years after treatment. They reported
results for patients who stayed in treatment less than 3 months and
for patients who received treatment for more than 3 months. Our
current discussion will focus on the latter group. Relative to
usage in the pre-period, the TOPS studies reported a significant
decline in cocaine, heroine, psychotherapeutic drugs, and marijuana
during the treatment and post-treatment periods. The results varied
across the different modalities and we shall examine the specific
outcomes below. The TOPS studies reported that heavy alcohol use
declined significantly during treatments, but it almost returned to
pre-period rates shortly after treatment.
Based on self-reported data, TOPS found
that predatory criminal activity (robbery, burglary, larceny, etc.)
declined significantly from pre-treatment levels during and after
treatments. The declines varied across the modalities and will be
discussed later.
One of the goals of drug abuse
treatments is to get drug abusers back to work and perhaps increase
their earnings. Several TOPS studies examined this issue. Hubbard
(1989) examined the effects of treatments on full-time employment
defined as working 35 or more hours per week for at least ¾ of the
weeks in the period. He reported a small but significant increase
in employment between the pre-treatment period and the 5 year
follow-up for residential and outpatient drug-free patients, but not
for outpatient methadone patients. Several later studies based on
TOPS data and using multivariate statistical analysis reported that
drug abuse treatments have a small but statistically significant
negative effect on illegal earnings and a small positive effect on
legal earnings and employment (French, Rachal, Harwood, and Hubbard
1990; French, Zarden, Hubbard, and Rachal 1991; ad. French and
Zarkin 1992).
After reviewing the existing literature
and noting the absence of the “ideal” control group, Anglin and Hser
(1990), concluded “research on drug abuse treatment demonstrates
significant declines in drug use and criminal behavior by
drug-dependent clients as a result of treatment” (p. 443). In their
review of the literature, McLellan, Woody, and Metzger (1991)
concentrated “on the studies that have used the most rigorous
evaluation methods, including random patient assignment, an
intent-to-treat design and data collection by independent
evaluation, the same standards and methods that are typically
applied by the FDA in evaluating new drugs and medical devices” (p.
84). They concluded that substance abuse treatments dramatically
reduce alcohol and drug use, improve patient’s medical and
psychological function, sometimes improve earnings from employment
and reduce utilization of medical and social services, and reduce
AIDS risk behaviors and drug-related crime. The authors stress that
these outcomes are found both in controlled clinical trials of
experimental interventions and in large-scale (i.e., DARP and TOPS)
evaluations of standard treatments in “real world” settings (p.
84). The NIDA (1999) echoed these sentiments a few years later.
The institute contends that drug addiction treatment is as
successful as treatment of other chronic diseases such as diabetes,
hypertension, and asthma. According to them, research shows that
drug treatment reduces drug use by 40 to 60% and significantly
decreases criminal activity during and after treatment by 40% or
more. Treatments also reduce the risk of HIV infection and improve
the prospects for employment.
Finally DATOS (2003) one-year
follow-ups indicted that drug abuse treatments reduced drug use,
illegal activities, and psychological distress on average by 50%.
The success rate varied across the different modalities, which will
be discussed below. Some patients also experienced a 10% increase
in full-time employment. The results from the DATOS (2003d) 5-Year
Outcomes were not quite as promising. Weekly cocaine use was
reported by 25% of the sample in the fifth year of follow-up,
slightly higher than the 21% for the first year after treatment.
Illegal activity was 25% in the fifth year compared to 16% in the
first year after treatment, but this is still well below the 40%
level at intake. Based on these studies, it must be concluded that
some drug abuse treatments are effective and that effectiveness
varies across treatment modalities.
6.4.2 The Effectiveness of Treatment
Modalities
We shall begin with a discussion of the
four historically important treatment modalities and then consider
the effectiveness of newer modalities.
(1)
Methadone Maintenance Programs
Early on, it was learned that
methadone maintenance treatments for opioid addicts led to a
significant reduction in the use of those drugs (Cooper et al.
1983). DARP studies confirmed this result. Because DARP considered
multiple outcomes, they defined two types of outcomes for purposes
of analysis: (1) highly favorable outcomes are defined as no
use of illicit drugs (except for less-than-daily marijuana use) and
no arrests–or- incarcerations in any one or more months during the
year and (2) moderately favorable outcomes are defined as no
daily use of illicit drugs and no major criminality (i.e., no more
than 30 days collectively in jail or in prison, and no arrests for
crimes against persons or crimes of profit) (Simpson 1984). These
two outcomes are well below the pre-treatment levels of drug use and
criminal activity levels. At the end of the first year after
treatment in methadone maintenance programs, it was reported that
27% of white males had a highly favorable outcome and 41% of
black males had a moderately favorable outcome.
The results for methadone maintenance
programs in the TOPS studies were also favorable, as indicated in
Table 6.1. The percentage of drug use for each of the four drugs
declined significantly for methadone patients from the one-year
pre-period to the 4
Table 6.1
Changes in Drug Abuse in the TOPS Study
By Modality and Treatment Duration
|
|
Outpatient
Methadone |
Residential |
Outpatient
Drug-Free |
|
<3
Months |
>3
Months |
<3
Months |
>3
Months |
<3
Months |
>3
Months |
|
|
% |
% |
% |
% |
% |
% |
|
Regular heroin use
1 year before
3 months in treatment
3-month follow-up
1-year follow-up
2-year follow-up
3-to-5 year follow-up |
65.0
--
25.3
31.2
21.7
24.9 |
63.5
5.9
16.0
16.7
14.9
17.5 |
30.5
--
14.2
16.8
7.8
12.2 |
30.9
0.3
10.7
11.5
13.2
11.8 |
11.5
--
7.7
9.1
4.5
5.2 |
8.6
3.0
5.1
4.9
4.9
4.6 |
|
Regular cocaine use
1 year before
3 months in treatment
3-month follow-up
1-year follow-up
2-year follow-up
3-to-5-year follow-up |
30.2
--
23.2
19.3
15.8
9.3 |
26.4
9.4
17.4
17.5
12.0
16.5 |
29.4
--
16.5
19.1
10.0
21.8 |
27.6
0.1
12.9
15.5
8.0
9.6 |
17.0
--
13.6
10.8
7.3
12.5 |
12.8
3.5
9.0
8.1
2.9
5.6 |
|
Regular non-medical psychotherapeutic use
1 year before
3 months in treatment
3-month follow-up
1-year follow-up
2-year follow-up
3-to-5-year follow-up |
35.3
--
24.7
22.1
15.3
11.4 |
30.3
12.0
26.9
21.7
13.1
10.2 |
52.2
--
29.7
31.4
19.6
14.9 |
49.9
1.3
16.4
9.4
9.4
9.3 |
41.1
--
27.3
27.1
23.5
11.9 |
35.7
11.8
18.9
16.1
12.0
4.4 |
|
Regular marijuana use
1 year before
3 months in treatment
3-month follow-up
1-year follow-up
2-year follow-up
3-to-5-year follow-up |
62.4
--
52.3
50.1
40.4
33.5 |
55.0
46.9
43.6
45.6
44.3
36.4 |
67.1
--
52.0
54.4
48.4
38.5 |
64.4
5.1
47.0
42.0
42.1
38.8 |
70.9
--
57.8
57.5
45.5
45.5 |
61.5
46.6
42.6
46.0
38.7
31.0 |
Source: Hubbard et al. (1989, p. 181).
post-periods. For example, for MM patients
having 3 months or more of treatments, the percentage of regular
heroin users declined from 63.5% in the pre-treatment period to
16.7% at the one-year follow-up. This represents a 73.7% decrease
in drug use. In the 3-to-5 year follow-up, the figure had risen
slightly to 17.5%. Even MM patients with less than 3 months of
treatment experienced a significant decline in drug use. For this
group, the percentage of regular heroin users declined from 65.0% in
the pre-period to 31.2% in the one-year follow-up and 24.9 in the
3-to-5 year follow-up.
TOPS MM patients with 3 or more months
of treatments also experienced a decline in criminal activity in the
post-treatment period. In this group, the percentage of patients
engaging in predatory crimes was 31% in the pre-period and only
about 19% in the one-year follow-up (a 39% decline) and in the
3-to-5 year follow-up it had declined further to about 17% (Hubbard
1989). Employment gains were more modest for the TOPS MM patients
with 3 or more months of treatment. This group’s percentage of
full-time employment was 24.2 in the pre-period. It declined to 20%
in the first year follow-up and then rose to nearly 30% in the
second year follow-up. In the 3-5 year follow-up it was 17.7%,
which was below the pre-treatment level (Hubbard et al. 1989).
Anglin and Hser (1990) were also sold
on the effectiveness of methadone maintenance in reducing drug use
and criminality. They were particularly impressed by two natural
experiment studies that investigated the effects of the termination
of two different methadone maintenance programs, which they had
conducted. NIDA (1999) reviewed the literature on methadone
maintenance programs and narcotic antagonist treatment programs
using naltrexone and concluded that naltrexone can help patients
hold jobs, avoid crime and violence, and reduce their exposure to
HIV. Finally, DATOS (2003b) reported that a one-year follow-up of
outpatient methadone treatment showed a 47.6% reduction in cocaine
use, a 68.5% reduction in heroin use, a 6.6% increase in heavy
alcohol use, a 51.7% reduction in illegal activity, and a 3.5% gain
in full-time work compared with pre-treatment levels.
(2)
Long-Term Residential Drug Free Programs
DeLeon (1984) was the first to
survey the literature on the effectiveness of therapeutic
communities (TCs) or long-term residential drug free programs. He
only considered published studies of traditional TC programs that
had at least 12 months of planned treatments. He reported that
immediate and long-term status of clients in terms of drug use and
criminality declined significantly, while measures of employment
and/or school involvement increased. DeLeon did not provide any
quantitative estimates of the average outcome effects for the
programs surveyed. He cautioned, however, that these conclusions
should be regarded as tentative because of serious methodological
problems. The studies did not include a control group and the
follow-up samples may be self-selected to seek, remain in and
benefit from TC; or, perhaps, to improve without any treatment.
DARP studies also reported favorable
outcomes for TCs. At the first year follow-up, 28 percent of adult
white male TC patients were reported to have highly favorable
outcomes and 40% of adult black males to have moderately
favorable outcomes, as defined above (Simpson 1984).
The TOPS data also showed that
residential programs are highly affected. As shown in Table 6.1,
there was a significant decline in residential patients use of all
four drugs following treatment. For example, for those patients
having 3 or more months of treatment, the percentage of regular
heroin users declined from 30.9% in the year prior to treatment to
11.5% at the 1-year follow-up and to 11.8% at the 3-to-5 year
follow-up. Even those patients having less than 3 months of
treatment reported significant declines in drug use at the 1-year
and 3-to-5 year follow-ups.
Criminal activity also declined for
TOPS residential patients following treatment. A little over 60% of
residential patients engaged in predatory crime before treatment.
At the first year follow-up, less than 30% reported doing so and in
the 3-to-5 year follow-up only 20% reported such activity (Hubbard
et al. 1989).
TOPS residential patients having more
than 3 months in treatments showed significant gains in long-term
employment. The percentage of patients working full-time prior to
treatment was 15.3%. At the first-year follow-up, it had risen to
25% and in the 3-to-5 year follow-up it was 38%.
Subsequent review studies confirm the
effectiveness of TCs. Citing DARP, TOPS, and other studies, Anglin
and Hser (1990) concluded that TCs reduce patient’s drug use and
criminal activity and increase their employment and social
behavior. DATOS (2003e) reported favorable outcomes for patients in
long-term residential treatment. From the pre-period to the
first-year follow-up cocaine use declined 66.7%, heroin use declined
64.7%, heavy alcohol use declined 52.5%, illegal activity fell 60.9%
and full-time employment rose 12.5%.
(3)
Outpatient Drug Free Treatment
DARP data indicated favorable outcomes
for outpatient drug free treatment. At the first year follow-up,
24% of adult white males had highly favorable outcomes and
33% of adult black males had moderately favorable outcomes
(Simpson 1984).
TOPS data for patients with 3 months or
more treatment in outpatient drug-free treatment also showed
favorable outcomes. As reported in Table 6.1, drug use declined for
all 4 drugs following treatment. The percentage of regular heroin
use declined from 8.6% in the year prior to treatment to 4.9% in the
first year follow-up and to 4.6% in the 3-to-5 year follow-up.
Table 6.1 also shows that outpatient drug-free patients having less
than 3 months of treatment also reported significant declines in
drug use in the post-period follow-ups.
TOPS data also show a reduction in
predatory crime activity for outpatient drug-free patients having
more than 3 months of treatment. For this group, the predatory
crime rate was 33% in the year before treatment. It declined to 19%
in the first year follow-up and to 8% in the 3-to-5 years follow-up
(Hubbard et al. 1989).
TOPS data showed highly significant
gains in employment for this group as well. The percentage of
patients in full-time employment rose from a pre-treatment level of
27% to 38% in the first year follow-up and to 49% in the 3-to-5
years follow-up (Hubbard et al. 1989).
DATOS data also confirm the
effectiveness of outpatient drug-free treatments. From the
pre-period to the first year follow-up, DATOS outpatient drug-free
treatment patients experienced a 57.1 decrease in cocaine use, a
64.0% decrease in marijuana use, a 51.6% decrease in heavy alcohol
use, a 36.4% decrease in illegal activity, and a 7.3% increase in
full-time work (DATOS 2003e).
(4)
Detoxification Programs
It was concluded early on that
outpatient or inpatient detoxification treatments produce no lasting
effects for those addicted to opioids (Cooper et al. 1983).
However, this treatment is effective in reducing drug use
temporarily and there is a demand for it (Anglin and Hser 1990).
Furthermore, as Senay (1984) points out from a clinical point of
view, detoxification programs are needed to treat emerging episodes,
reduce the length and severity of “runs” and attract addicts into
the treatments system generally. A recent NIDA (1999) study echoed
these sentiments.
(5)
Criminal Justice Treatment Programs and Clients
Anglin and McGlothlin (1984) summarized
the results their research group obtained from evaluations of the
California Civil Addict Program (CAP). They used a pre/post time
series design with a matched comparison group. They found evidence
of positive “ramp up” effects in the pre-period for drug use and
criminal activity and negative “ramp-down” effects for employment.
They find strong evidence that CAP effectively reduces drug use and
crime, and to a lesser extent, increases employment and family
responsibility. The strength of their findings was supported by two
natural experiment studies that analyzed the effects of closing two
methadone maintenance treatment programs.
The TOPS study analyzed the effects of
drug abuse treatments on clients who were referred to outpatient
drug-free or residential treatment programs under the Treatment
Alternatives to Street Crimes (TASC) Act. The TOPS data indicated
that in terms of reductions in drug use and criminal activity, the
criminal justice clients do as well or better than other clients in
drug abuse treatment (Hubbard et al. 1989).
After reviewing the relevant
literature, Anglin and Hser (1990) concluded clients entering
treatment under legal coercion do as well by most outcome criteria
as volunteer clients and may stay in treatment longer. They
specifically referred to the evidence from the evaluations of
criminal justice civil commitment programs conducted by Anglin and
McGlothlin (1984). Anglin and Hser also reported that research
results indicate that correctional drug-treatment programs can have
a substantial effect on the behavior of chronic drug-abusing
offenders.
Along these same lines, NIDA (1999)
reported that research has shown that combining criminal justice
sanctions with drug treatments can be effective in decreasing drug
use and related crime. They also reported that prison-based
treatment programs can be effective if patients are separated from
the general prison population and if they continue treatment after
returning to the community. Finally, NIDA (1999) concluded that
individuals who enter treatment under legal pressure have outcomes
as favorable as those who enter treatment voluntarily.
(6)
Short-Term Inpatient (STI) Treatment
DATOS data showed that patients
receiving short-term inpatient treatments have favorable outcomes.
First year follow-ups showed a 69% drop in the number of weekly
cocaine users, a 63% reduction in the number of weekly marijuana
users, a 58% decline in heavy drinkers, and an insignificant 4.5%
increase in full-time work (DATOS 2003e).
6.4.3
The Relative Effectiveness of Treatment Modalities
Simpson (1984) noted that the DARP
outcome differences reported for methadone maintenance, therapeutic
communities, and outpatient drug-free treatment programs were not
statistically significant. He noted there were significant
differences in the types of clients served and in the dropout rates
in the programs. For instance, methadone maintenance frequently
deals with older addicts with longer histories of opioid use and
criminal involvement and the treatment strategy is designed to deal
with these historical entrenched behavioral patterns. Tims and
Holland (1984) argued that few meaningful differences are likely to
be found in outcomes among treatment modalities that are not either
a function of client differences or of time in treatment. They also
noted that attempts to randomly assign well-defined homogenous
client pools to modalities have been frustrated by clients crossing
over to their treatment of choice or withdrawing from treatment (see
also Hall 1984). Finally, Anglin and Hser (1990) also concluded
that comparisons between modalities are necessarily restricted
because no two modalities necessarily have similar client
populations. We know that outcomes are correlated with patient’s
problems and characteristics.
6.4.4
Patient Characteristics and Outcomes
The drug abuse treatment population is
heterogeneous; clients are not characterized by a common set of
demographics or problems. They vary in age, gender, race, social
and economic background, drug-dependence, health status, and
psychological well being (Hubbard et al. 1989). They have different
criminal and treatment histories. The literature indicates that
some of these factors are highly correlated with post-treatment
successful outcomes. Jaffe (1984), DeLeon (1984) and McLellan,
Woody, and Metzger (1996) concluded in their reviews that a stable
family background has a positive affect on drug abuse patients’
favorable outcomes. Anglin and Hser (1990) reported that having an
intact marriage also has a positive impact on drug abuse treatment
outcomes. They further concluded that having a job was positively
correlated with favorable outcomes.
Jaffe (1984), Simpson (1984), and
DeLeon (1984) reported that drug abuse patients having a more
extensive criminal history are likely to report less favorable
outcomes. DeLeon (1984) reported that drug abusers with more
extensive history of treatment fared as well as other patients, but
Franey and Ashton (2002) reported they fared less well.
The severity of drug dependence and the
extent of drug use are reported to be negatively correlated with
drug abuse treatment favorable outcomes (Simpson 1984 and McLellan,
Woody, and Metzger (1996). Drug addicts that use alcohol or poly
drug use are likely to have less favorable outcomes as well (Anglin
and Hser 1990).
Finally, a number of studies have
reported the greater the severity of the psychiatric disorder at
intake, the less favorable the treatment outcomes for drug abusers
(Jaffe 1984, DeLeon 1984, Anglin and Hser 1990,McLellan, Woody, and
Metzger 1996, and DATOS 2003d). McLellan, Woody, and Metzger (1996)
added that treating drug abusers having an antisocial personality
diagnosis is particularly problematic.
Given these findings, it is important
to gather information on the |